Analysis of pharmacokinetic data by wilk’s lambda (An important tool of manova)
نویسندگان
چکیده
In the present research article, we applied Wilks Lambda on two different pharmacokinetic studies. In the first study we check the bioavailability of the three different formulations (Dynapar QPS). We check the effectiveness of these formulations using Wilks Lambda. We found no significant difference in the effectiveness as measured by pharmacokinetic parameters. For the second study, we test the significance effects of the two drugs (reference and test), of three different formulations and with their interaction affects using Wilks Lambda. We found no significant difference on pharmacokinetic parameters (Cmax, Tmax), formulations and interaction.
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